Cross-priming is an important mechanism to activate cytotoxic T lymphocytes (CTLs) for immune defence against viruses and tumours. Although it was discovered more than 25 years ago, we have only recently gained insight into the underlying cellular and molecular mechanisms, and we are just beginning to understand its physiological importance in health and disease. Here we summarize current concepts on the cross-talk between the immune cells involved in CTL cross-priming and on its role in. Cross-priming in health and disease. Source: NCBI PubMed ( ID PMID:20498667) IF:40.358 Cited:186 Endnote Download. Kurts C 1, Robinson BW, Knolle PA. Kurts C.
Cross-priming. Cross-priming refers to the stimulation of antigen-specific CD8+ cytotoxic T lymphocytes (CTLs) by dendritic cell presenting an antigen acquired from the outside of the cell. Cross-priming is also called immunogenic cross-presentation. This mechanism is vital for priming of CTLs against viruses and tumours In Experiment 2, the same cross-modal priming paradigm was used with ambiguous words presented as primes (e.g., BANK) and either high-dominant (e.g., MONEY) or low-dominant (e.g., RIVER) words as targets. The results of Experiment 2 produced a qualitatively distinct pattern of priming that indicated DAT individuals only produced priming for high-dominant targets and not for low-dominant targets, whereas, the healthy control groups produced equivalent priming for both high- and low.
Cross-priming in health and disease. Access Restriction Subscribed. Author: Kurts, Christian ♦ Robinson, Bruce W. S. ♦ Knolle, Percy A. Source: World Health Organization (WHO)-Global Index Medicus: Content type: Text: File Format: HTM / HTML: Language: English: Age Range: above 22 year: Education Level: UG and PG: Learning Resource Type : Article: Publisher Date: 2010-06-01: Cross-priming. Article Cross-priming in health and disease Detailed information of the J-GLOBAL is a service based on the concept of Linking, Expanding, and Sparking, linking science and technology information which hitherto stood alone to support the generation of ideas. By linking the information entered, we provide opportunities to make unexpected discoveries and obtain knowledge from dissimilar. Cross-priming is also called immunogenic cross-presentation.This mechanism is vital for priming of CTLs against viruses and tumours Immune priming (invertebrate immunity). Remove this presentation Flag as Inappropriate I Don't Like This I like this Remember as a Favorite. Furthermore, human tumor studies have demonstrated that both macrophages and DCs can take up antigens in vitro and prime. 摘要： Cross-priming is an important mechanism to activate cytotoxic T lymphocytes (CTLs) for immune defence against viruses and tumours. Although it was discovered more than 25 years ago, we have only recently gained insight into the underlying cellular and molecular mechanisms, and we are just beginning to understand its physiological importance in health and disease Fig. 2. Potential distinctions between the semantic structures for unambiguous targets (top panel) and ambiguous targets (bottom panel). Arrowed pathways (i.e., a) reflect facilitatory connections, whereas, segmented pathways (i.e., ) reflect inhibitory connections. - Cross-modal semantic and homograph priming in healthy young, healthy old, and in Alzheimer's disease individuals
Cross-priming in health and disease Published in: Nature Reviews Immunology, June 2010 DOI: 10.1038/nri2780: Pubmed ID: 20498667. Authors: Christian Kurts, Bruce W. S. Robinson, Percy A. Knolle View on publisher site Alert me about new mentions. Mendeley readers. The data shown below were compiled from readership statistics for 471 Mendeley readers of this research output. Click here to see. Cross-modal semantic and homograph priming in healthy young, healthy old, and in Alzheimer's disease individuals DAVID A. BALOTA,1 JASON M. WATSON,1 JANET M. DUCHEK,1 and F. RICHARD FERRARO 2 1 Department of Psychology, Washington University, St. Louis, MO 2 Department of Psychology, University of North Dakota, Grand Forks, ND (Received October 15, 1998; Revised March 24, 1999; Accepted June 1, 1999) Abstract Two experiments are reported that explore the influence of strength of the prime.
Cross-tissue integration of scRNA from monocytes and macrophages in health and disease • Conserved gene signatures of mononuclear phagocyte populations in human tissues • IL4I1 + PD-L1 + IDO1 + and TREM2 + TAM subsets accumulate in human tumors • IL4I1 + PD-L1 + IDO1 + TAM in the tumor periphery exhibit immunosuppressive characteristics. Summary. Mononuclear phagocytes (MNPs) encompass. Neutrophil priming, including shape change, has been shown to be reversible in vitro, however, there are limited data about the effects of priming on neutrophil kinetics in vivo. Up to 15% of the cardiac output can pass through an inflamed site (as observed in patients with active inflammatory bowel disease), therefore, all neutrophils are expected to be exposed to the priming stimulus within. The impact of trained immunity, and more generally of epigenetic rewiring in various processes of priming, adaptation or tolerance during disease 111, warrants further studies. Also, the role of. Twenty patients at early stages of Alzheimer's disease (AD), 20 elderly control subjects and 20 young subjects completed a cross-form priming task, followed by a free recall task. Results show that patients with mild AD display priming effects, and that these priming effects are strictly comparable to those obtained by elderly and young control subjects. Moreover, while the patients. Cross-priming in health and disease Kurts, Christian, Robinson, Bruce W. S., Knolle, Percy A. How much do you like this book? What's the quality of the file? Download the book for quality assessment. What's the quality of the downloaded files? Volume: 10. Year: 2010. Language: english. Pages: 12. DOI: 10.1038/nri2780. File: PDF, 534 KB. Send-to-Kindle or Email . Please to your.
This is true even in the absence of direct infection of these cells, which indicates that cross-priming is an essential component of the immune response against pathogens. Original language: English: Pages (from-to) 437-41: Number of pages: 5: Journal : Current Opinion in Immunology: Volume: 13: Issue number: 4: Publication status: Published - Aug 2001: Cite this. APA Author BIBTEX Harvard. Cross-priming amplification targeting the 18S rRNA gene for the rapid diagnosis of Babesia bovis These diseases have diverse impacts on human health and the livestock industry throughout the world and impedes improvements in quality of life, especially in developing countries. Since the first case of babesiosis was described in cattle by Babes in 1888, over 100 Babesia species have been.
Knutsson A: Shift work and coronary heart disease. Scand J soc Med. 1989, 1-36. Suppl 44. 18. Kitahara K, Sungkim IL, Yoshizumi K: Survey on the health indices and life style related to work system in manufacturing companies: effect of changed work system on health indices. Shift work international news letter. 1999, 16-73 .
Significant cross-modal priming occurred when modality changed from taste-to-smell in young and healthy older adults. Importantly, although within-modal and cross-modal priming persist, stimulus identification decreases with age and cognitive status. Importantly, cross-modal taste-to-smell identification did not differ from zero in the MCI group, indicating that their performance was at chance. Understanding metabolic cross-talk in health and disease - Focus on type 2 diabetes and fatty liver Research Project Leader Dr Magdalene Montgomery. firstname.lastname@example.org. View researcher's webpage +61 422 059 907. Project Details The concept of 'metabolic cross-talk' postulates that tissues secrete factors that act through paracrine and/or endocrine communication to alter. Experiment 2 showed cross-modal taste to olfactory priming in young adults and healthy older people, but the performance of older adults with MCI did not differ from zero. Again, identification decreased significantly in older adults and was absent in those with MCI .e., greater tolerance to a second stronger stress after exposure to a different or similar mild primary stress) have attracted considerable interest from the scientific community as a potential means of stress management and also for producing stress-resilient crops in order to aid with sustaining global food security. Since then.
Perceptual-identification priming paradigms shall be preserved and conceptual-production priming paradigms impaired. A third interpretation is yet possible based on the disconnection syndrome hypothesis which states that patients with AD should fail tasks requiring relatively complex brain communications. In this case, patients with AD should not demonstrated a significant perceptual priming. In the current cross-sectional serosurveillance study performed in 2016-2017, we investigated the change in seroepidemiology ten years after the previous serosurvey and whether changes were possibly related to the switch from wP to aP priming in 2005 or to the in 2001 implemented aP booster vaccination at 4 years of age. Other possible influencing factors, like religion, were also analysed Cross-priming was surprisingly efficient, whether antigen was restricted to the hematopoietic or nonhematopoietic compartments. CD8 cells were exclusively primed by donor CD11c + cells, and optimal cross-priming required they be stimulated by both type I IFNs and CD40L. In studying which donor APCs acquired host miHAs, we made the surprising. The present study builds upon these previous findings by examining whether non-linguistic rhythmic priming also influences visual word processing, and the extent to which such cross-modal priming effect of rhythm is related to individual differences in musical aptitude and reading skills. An electroencephalogram (EEG) was recorded while participants listened to a rhythmic tone prime, followed. [en] Twenty patients at early stages of Alzheimer's disease (AD), 20 elderly control subjects and 20 Young subjects completed a cross-form priming task, followed by a free recall task. Results show that patients with mild AD display priming effects and that these priming effects are strictly comparable to those obtained by elderly and young control subjects. Moreover, while the patients.
Disease Activity and Mental Health in SLE Patients: A Cross-section Study with Self-Assessments Based on Smart System of Disease Management (SSDM) Mobile Tools . Yongfu Wang 1, Hua Wei 2, Rui Wu 3, Jianhong Wu 4, Shengtao Zhang 5, Qin Li 6, Yang Li 7, You Sun 7, Yanping Zhao 8, Qiang Shu 9, Lirong Kang 1, Bin Wu 10, Li Qin 11, Feng Jiang 11, Huiqin Yang 12, Junli Zhang 13, Hui Xiao 14, Bing Wu. Scale drop disease virus (SDDV) is one of the most important pathogens that causes scale drop disease (SDD) in Asian sea bass (Lates calcarifer). The outbreaks of this disease are one of the factors causing substantial losses in Asian sea bass aquaculture. In this study, the uracil-DNA glycosylase (UDG)-supplemented cross-priming amplification (UCPA) combined with a colorimetric detection.
African swine fever (ASF) is considered a major threat to the production of pigs worldwide. The ASF aetiological agent, ASFV, is the sole member of the Asfivirus genus, belonging to the Asfarviridae family. An effective ASF vaccine is not currently available, thus the only measures of ASF spread control include, reliable and fast diagnosis. Officially approved, diagnostic methods include. We employed a vaccine approach based on a mixture of peptides (pepmix) spanning the entire sequence of HCV nonstructural protein 3 (NS3) in cross-priming cationic liposomes (CAF09) to facilitate a versatile presentation of all possible T cell epitopes, regardless of the HLA background of the vaccine recipient. Here, we demonstrate that vaccination of mice with NS3 pepmix broadens the. MEPs are ready to negotiate with member states to reinforce the EU's disease prevention and control framework and jointly tackle cross-border health threats. The proposal to extend the mandate of the European Centre for Disease Prevention and Control (ECDC) was adopted with 598 votes in favour, 84 against and 13 abstentions Development of cross-priming amplification assays for rapid and sensitive detection of Aeromonas hydrophila. Meng, S.; Meng, S. Search for other works by this author on: This Site. Wang, Y.; Wang, Y. Search for other works by this author on: This Site. Wang, Y.; Wang, Y. Search for other works by this author on: This Site. Liu, D.; Liu, D. Search for other works by this author on: This Site.
Globalization and Health invites you to submit to our article collection on cross-border infectious disease threat, and the national and global public health response. We welcome submissions on the subject of COVID-19 to this collection. In order to be considered, manuscripts must address health systems issues and fall within one of these categories: An analysis or discussion of measures taken. Making Sense of Health, Disease, and the Environment in Cross-Cultural History: The Arabic-Islamic World, China, Europe, and North America. Editors: Bretelle-Establet, Florence, Gaille, Marie, Katouzian-Safadi, Mehrnaz (Eds.) Free Preview. Provides a multi-spatial and historical approach to the issue of environment, health and disease ; Enlarges the analysis beyond the traditional disciplinary. Detection of Chlamydia trachomatis and Neisseria gonorrhoeae based on cross-priming infections may result in serious secondary complications, such as pelvic inflammatory disease, ectopic pregnancy and infertility (Cates and Wasserheit 1991; Paxton et al. 1998). Based on a World Health Organization report, approx. 105 million C. trachomatis and 106 million N. gonorrhoeae cases are globally.
Background: Wheatgrass ( Triticum aestivum L.) is worldwide consumed and has been used for health benefit or functional or nutraceutical food while ricegrass ( Oryza sativa L.) is still not well documented, which is also in the grass family (Poaceae) as wheatgrass and it is also produced with aged around 8-10 d which similar to wheatgrass production. Moreover, priming is a process for. Am J Public Health. 2017; 107:582-589. doi: 10.2105/AJPH.2016.303648 Crossref Medline Google Scholar; 18. Nokoff NJ, Scarbro S, Juarez-Colunga E, Moreau KL, Kempe A. Health and cardiometabolic disease in transgender adults in the United States: behavioral risk factor surveillance system 2015. J Endocr Soc Iain Stephenson, Roberto Bugarini, Karl G. Nicholson, Audino Podda, John M. Wood, Maria C. Zambon, Jacqueline M. Katz, Cross-Reactivity to Highly Pathogenic Avian Influenza H5N1 Viruses after Vaccination with Nonadjuvanted and MF59-Adjuvanted Influenza A/Duck/Singapore/97 (H5N3) Vaccine: A Potential Priming Strategy, The Journal of Infectious Diseases, Volume 191, Issue 8, 15 April 2005, Pages.
Cross-sectional data were analysed for 824,694 children surveyed in 54 Demographic and Health Surveys, 21 Malaria Indicator Surveys, and two AIDS Indicator Surveys conducted in 33 countries between 2001 and 2017 that measured malaria infection by microscopy or rapid diagnostic test (RDT), diarrhoea, acute respiratory infections (ARIs), stunting, wasting, underweight, or anaemia in children. Alzheimer's disease Implicit memory Cross-modal priming Disconnection syndrome abstract Implicit memory is generally supposed to be preserved in Alzheimer's disease (AD). Yet, some implicit priming effects are impaired and others are not. The preserved/impaired priming effects are often interpreted according to the perceptual/conceptual or identiﬁ- cation/production distinctions.
Development of cross-priming amplification (CPA) combined with colorimetric and lateral flow dipstick visualization for scale drop disease virus (SDDV) detection. PMID: 34041757 (view PubMed database entry) DOI: 10.1111/jfd.13448 (read at publisher's website ) Terawut Prasitporn, Saengchan Senapin, Akapon Vaniksampanna, Siwaporn Longyant, Parin Chaivisuthangkura, Scale drop disease virus (SDDV. The vaccine elicitation of broadly neutralizing responses is a central goal of HIV research. Recently, we elicited cross-clade neutralizing responses against the N terminus of the fusion peptide (FP), a critical component of the HIV-entry machinery. While the consistency of the elicited cross-clade neutralizing responses was good in mice, it was poor in guinea pigs: after seven immunizations. The team at Children's Health Defense decided to write an article about Dengue Fever because an important part of medicine's body of knowledge comes from the opportunity to learn from past mistakes. Dengue fever is a common disease in more that 120 countries and, like Coronavirus, has been the target for a vaccine for many years As public health professionals, we all should be working across a variety of fields and engaging a variety of partners and communities to develop the very best solutions to our health problems. As an epidemiologist, I am committed to creatively considering all possibilities in understanding disease and implementing effective interventions that help local and global communities thrive Health and disease are critical concepts in bioethics with far-reaching social and political implications. For instance, any attempt to educate physicians or regulate heath insurance must employ some standards that can be used to assess whether people are ill or not. Concepts of health and disease also connect in interesting ways with issues about function and explanation in philosophy of the.
The document provides and introduction to disease, the types of fish diseases and what to do if fish are sick. Water quality Environment Biosecurity Health. by Banrie 25 February 2013, at 12:00am What is fish health management? Fish health management is a term used in aquaculture to describe management practices which are designed to prevent fish disease. Once fish get sick it can be difficult. Lipid management in India: a nationwide, cross-sectional physician survey. Gurpreet S. Wander 1, Uday M. Jadhav 2, Amruta Chemburkar 3, Meena Lopez 3 & Jaideep Gogtay 3 Lipids in Health and Disease volume 16, Article number: 130 (2017) Cite this articl
Intact haptic priming in normal aging and Alzheimer's disease: evidence for dissociable memory systems. Neuropsychologia, 2004. Soledad Ballesteros. Download PDF. Download Full PDF Package. This paper. A short summary of this paper . 37 Full PDFs related to this paper. READ PAPER. Intact haptic priming in normal aging and Alzheimer's disease: evidence for dissociable memory systems. Plesiomonas shigelloides (P. shigelloides) is implicated as an aetiological agent of human gastroenteritis in humans, for which reliable laboratory detection of P. shigelloides is clinically and epidemiologically desirable. A simple molecular method for rapid detection of P. shigelloides using cross‑priming amplification (CPA) has been developed, with hugA as the target P. Mark Bartold, Periodontal tissues in health and disease: introduction, Periodontology 2000, 40, 1, (7-10), (2006). Wiley Online Library Ira B. Lamster , Antimicrobial mouthrinses and the management of periodontal diseases , The Journal of the American Dental Association , 137 , (S5) , (2006)
Health is fundamental for a good quality of life. Being free from illness or injury directly affects our capacity to enjoy life. In this entry we provide an overview of the available empirical evidence on aggregate health outcomes, focusing on long-run cross-country data from mortality and morbidity tables; and then provide an analysis of available evidence on health determinants, focusing. High level of mastering the subject. Has been able to cover all requirements. Can count assignment The Purin Bodies Of Food Stuffs And The R%C3%B4le Of Uric Acid In.
Cross-Microbial Protection via Priming a Conserved Immune Co-Receptor through Juxtamembrane Phosphorylation in Plants. Ben-Qiang Gong . Ben-Qiang Gong. Affiliations. Guangdong Provincial Key Laboratory of Plant Resources, State Key Laboratory of Biocontrol, MOE Key Laboratory of Gene Function and Regulation, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China. Search for. Tuning up live-vaccine priming for infectious bursal disease and reovirus. An interview with Kalen Cookson, DVM, MAM, Director of Clinical Research, Zoetis. Poultry health Treatments and prevention Health & disease. by Laurence Williams 2 January 2020, at 10:59am Q: Why is live priming of breeder pullets for infectious bursal disease virus (IBDV) and reovirus important? KC: By initiating an. We compared 20 euthymic bipolar patients and 20 healthy subjects on their performance in subliminal and supraliminal tasks. Priming tasks consisted of three different primes according to facial emotions (happy, sad, and neutral) followed by a neutral face as a target stimulus. The prime stimuli were presented subliminally (17 msec) or supraliminally (1000 msec). In subliminal tasks, both.
Diseases and health threats. Health security and infectious diseases. European Centre for Disease Prevention and Control (ECDC) Vaccination. Antimicrobial resistance . Non-communicable diseases. Cancer. Mental health. Risk assessment. Scientific committees. Endocrine disruptors. Endocrine disruptors. Biocides. Biocides. Evaluation of the Cross-Border Healthcare Directive . Ten years after the. Health Topics Alzheimer's Disease Chronic Disease Prevention Section HIV/AIDS Injury Prevention Program The following training courses are offered as cross-training opportunities and are design to introduce Communicable Disease Specialists (CDS) to additional areas of infectious disease. CDS are encouraged to complete Hepatitis, TB, HIV and COVID-19 cross-training opportunities within the. Recent studies showed that dyslipidemia could be a critical factor in the progression of cardiovascular disease in systemic lupus erythematosus (SLE). The aim of the present study was to describe the relationship between serum lipid profile and SLE disease activity in young female adults with SLE. Seventy-one female subjects diagnosed with SLE aged 20~30 years were enrolled 1: Introduction; View more Opportunities for Heath Promotion and Disease Prevention in Rural Areas Rural programs are well positioned to implement successful health promotion and disease prevention strategies, despite facing challenges such as chronic disease, poverty, lower educational attainment, and access to transportation, among others Ms Irene Passaris, Director, Communicable Disease Control Section, Health Protection Service, ACT Health Directorate Ms Paula Spokes, A/Manager, Surveillance, Communicable Diseases Branch, Centre for Health Protection, NSW Ministry of Health Technical Writers Biotext, Canberra To obtain information regarding NHMRC publications contact: Email: email@example.com Phone: Toll free 13.
Sucrose-Mediated Priming of Plant Defense Responses and Broad-Spectrum Disease Resistance by Overexpression of the Maize Pathogenesis-Related PRms Protein in Rice Plants . Jorge Gómez-Ariza, Sonia Campo, Mar Rufat, Montserrat Estopà, Joaquima Messeguer, Blanca San Segundo, and ; María Coca; Jorge Gómez-Ariza. Search for more papers by this author , Sonia Campo. Search for more papers by. . Threats to biodiversity and health. There is growing concern about the health consequences of biodiversity loss. Biodiversity changes affect ecosystem functioning and significant disruptions of ecosystems can result in life sustaining ecosystem goods and services. Biodiversity loss also. Markers of Brain Health and Function. Markers of brain health and disease are key to understanding and treating neurological conditions. Development of sophisticated neuroimaging techniques [e.g., Positron Emission topography (PET) and functional Magnetic Resonance Imaging (fMRI)] has enabled subtle differences in brain activity, metabolism and structure to be monitored and distinguished.
. The right health care system interventions can improve the use and quality of clinical preventive services. These services can help prevent disease or catch it early, reduce risk factors, and manage complications. Giving people better access to quality preventive services can. Dental caries is a preventable childhood disease, but public health efforts are hampered due to limited information on associated factors in vulnerable populations. Our study was aimed at estimating the prevalence of dental caries and identifying key associated factors in four major risk domains, including socioeconomic factors, child oral health behavior and practices, child feeding practices. Study population, setting, and design. The Puerto Rico Assessment of Diet, Lifestyle, and Diseases (PRADLAD) study is a cross-sectional survey of a convenience sample of 380 adults living in Puerto Rico, conducted in 2015 with the goal of assessing lifestyle risk factors and health conditions among adults in the island
A cross-regulation between type I IFN and TNFα has been proposed recently, where both cytokines are hypothesized to counteract each other. According to this model, different autoimmune diseases can be viewed as disequilibrium between both cytokines. As this model may have important clinical implications, the present review summarizes and discusses the currently available clinical evidence. Cross-Sector Description. The NORA Respiratory Health Cross-Sector advances primary and secondary prevention addressing a range of hazardous exposures and their adverse respiratory health effects including lower airways diseases (e.g., asthma, chronic obstructive lung disease); upper airways diseases (e.g., rhinosinusitis); interstitial lung.
WHO is supporting countries to deliver integrated, evidence-based and cost-effective care for mothers and babies during pregnancy, childbirth and the postpartum period. Investing in health systems - especially in training midwives and in making emergency obstetric care available round-the-clock - is key to reducing maternal mortality . We provide pump-priming. Other health outcomes besides diseases may also be studied. Cross-sectional studies also differ from cohort studies in the populations that are studied. Cohort studies begin by selecting a population of persons who are at risk of for a specific disease or health outcome; cross-sectional studies begin by selecting a sample population and then obtaining data to classify all individuals in the.
Methods and analysis This cross-sectional study will include young and old individuals susceptible or non-susceptible to develop COPD. At a young age (18-40 years) 60 'party smokers' will be included who are called susceptible or non-susceptible based on COPD prevalence in smoking family members. In addition, 30 healthy smokers (age 40-75 years) and 110 COPD patients will be included. InfoNTD is the one-stop portal of information on cross-cutting issues in Neglected Tropical Diseases (NTDs), such as disease prevention, disease management, disability, inclusion, stigma, mental wellbeing, health education, mHealth and WASH. The ILEP/NNN Guides on Stigma and Mental Wellbeing are launched! Click on the link below to find out how you can help to end stigma. Go to Stigma Guides. Glomerular diseases include many conditions with a variety of genetic and environmental causes, but they fall into two major categories: Glomerulonephritis describes the inflammation of the membrane tissue in the kidney that serves as a filter, separating wastes and extra fluid from the blood. Glomerulosclerosis describes the scarring or. The Blue Cross Blue Shield (BCBS) Health Index quantifies over 300 different health conditions to identify which diseases and conditions most affect Americans' longevity and quality of life. It is powered by annual data from more than 41 million BCBS members, commercially insured Americans. BCBS companies are committed to improving Americans' health by providing data-driven insights to. Burden of disease focuses on health loss due to disease and injury. It does not account for other broader factors influencing health, such as the social and economic impacts of ill health. Top disease burdens. Find out more: Chapter 3.1 'Burden of disease across the life stages' in Australia's health 2018. Half of us have a chronic condition . Chronic conditions are generally long.
Read the latest research on diseases and conditions, symptoms, new treatment options and more. Updated daily Health.gov is your portal for health-related resources and news from the U.S. government. Find prevention topics, dietary and physical activity guidelines, and other health resources Background: Measuring physical activity with commercially available activity trackers is gaining popularity. People with a chronic disease can especially benefit from knowledge about their physical activity pattern in everyday life since sufficient physical activity can contribute to wellbeing and quality of life. However, no validity data are available for this population during activities of. The latest news on health and medicine, covid, vaccines, global health, mental health, Obamacare, health insurance, Medicare, Medicaid, opioids, cancer, heart disease.